Fundamental concepts in engineering materials for drug delivery. The human body is a highly interconnected network of different tissues and there are all sorts of barriers to getting pharmaceutical drugs to the right place at the right time. Topics include drug delivery mechanisms (passive, targeted), therapeutic modalities and mechanisms of action, engineering principles of controlled release and quantitative understanding of drug transport, chemical and physical characteristics of delivery molecules and assemblies, significance of biodistribution and pharmacokinetic models, toxicity of biomaterials and drugs, and immune responses.
3 units · Letter or Credit/No Credit
Fundamental concepts in engineering materials for drug delivery. The human body is a highly interconnected network of different tissues and there are all sorts of barriers to getting pharmaceutical drugs to the right place at the right time. Topics include drug delivery mechanisms (passive, targeted), therapeutic modalities and mechanisms of action, engineering principles of controlled release and quantitative understanding of drug transport, chemical and physical characteristics of delivery molecules and assemblies, significance of biodistribution and pharmacokinetic models, toxicity of biomaterials and drugs, and immune responses.
Offered in Winter 2027 at Stanford University.